MOTS-c 10mg
MOTS-c is a 16-amino-acid peptide encoded not in nuclear DNA but within the 12S rRNA region of the mitochondrial genome. That origin makes it one of the defining molecules in mitochondrial-derived peptide research.
- Mitochondrial-derived peptide, 16 amino acids
- Studied around AMPK activation and metabolic homeostasis
- Frequently referenced in exercise-adaptation literature
- Presentation
- 10 mg Vial
- Purity
- 99.71%
Sold strictly for in-vitro laboratory research. Not for human or veterinary consumption.
Research background
MOTS-c was identified through analysis of short open reading frames in mitochondrial DNA. Its discovery supported the idea that mitochondria issue signalling molecules to the rest of the cell, rather than only responding to nuclear instruction.
Published work has explored AMPK activation, insulin sensitivity, glucose handling, exercise capacity, and how expression changes under metabolic stress. Because levels shift with age and physical activity in some models, it also appears in ageing-biology literature.
Handling and storage
Lyophilised material is stable for extended periods when kept sealed, dry, and away from light. Long-term storage in research settings is commonly at -20°C, with short transit at ambient temperature considered acceptable for lyophilised powders.
Once reconstituted, solutions are refrigerated at 2-8°C and used within a limited window, as peptides in aqueous solution degrade far faster than in powder form. Repeated freeze-thaw cycles are avoided.
Reconstitution notes
Peptides in this catalogue are supplied lyophilised. In laboratory settings they are typically reconstituted with bacteriostatic or sterile water added slowly down the inside wall of the vial, never injected directly onto the powder pellet.
The vial is then left to dissolve on its own, or swirled gently. Vigorous shaking is avoided because mechanical shear can denature peptide chains and reduce measurable potency in subsequent assays.
Purity and batch testing
Every batch we list is accompanied by third-party analytical testing. The Certificate of Analysis linked on this page shows the lot number, HPLC purity trace, and mass spectrometry identity confirmation for the exact batch held in stock.
Purity figures quoted on this page are taken directly from that report rather than from a manufacturer datasheet, so what you read here matches the vial that ships.
Frequently asked questions
- What makes MOTS-c different from other research peptides?
- It is encoded by mitochondrial rather than nuclear DNA, which is why it is classed as a mitochondrial-derived peptide and studied in the context of mitochondrial signalling.
- Is this product for human consumption?
- No. Everything in the Fox Peptides catalogue is supplied strictly for in-vitro laboratory research use. It is not a medicine and is not for human or veterinary consumption.
- Do you provide a Certificate of Analysis?
- Yes. Each batch is third-party tested and the Certificate of Analysis for the lot currently in stock is linked directly on this page, showing HPLC purity and mass spectrometry identity confirmation.
- Where do you ship and how long does delivery take?
- We ship across the UK with tracked delivery. Orders are dispatched from the UK once payment clears, so there are no customs delays for UK customers.
- How do I pay?
- Checkout uses secure open-banking bank transfer. You approve the payment inside your own banking app, and your order is confirmed automatically once the transfer clears.